|
|
(S)-malate + NAD+ <=> oxaloacetate + NADH + H+
|
1.1.1.28
D-lactate dehydrogenase
1.1.1.299
malate dehydrogenase [NAD(P)+]
1.1.1.337
L-2-hydroxycarboxylate dehydrogenase (NAD+)
1.1.1.37
malate dehydrogenase
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.38
malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.81
hydroxypyruvate reductase
1.1.1.82
malate dehydrogenase (NADP+)
1.1.1.85
3-isopropylmalate dehydrogenase
1.1.1.95
phosphoglycerate dehydrogenase
1.1.1.96
diiodophenylpyruvate reductase
|
–
–
–
–
–
–
–
–
–
–
–
|
BMK
|
| |
BRENDA:
BR29300;
BS188027
KEGG:
R00342
MetaCyc:
MALATE-DEH-RXN;
RXN-10813_WOP
|
|
|
|
(S)-malate + NAD+ <=> pyruvate + CO2 + NADH
|
1.1.1.38
malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39
malate dehydrogenase (decarboxylating)
1.1.1.40
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85
3-isopropylmalate dehydrogenase
1.3.1.7
meso-tartrate dehydrogenase
|
–
–
–
–
–
|
BMK
|
| |
BRENDA:
BR29301;
BS188113
KEGG:
R00214
MetaCyc:
1.1.1.39-RXN;
RXN-19748
SABIO-RK:
141
|
|
|
|
(S)-malate + NADP+ <=> pyruvate + CO2 + NADPH
|
1.1.1.38
malate dehydrogenase (oxaloacetate-decarboxylating)
1.1.1.39
malate dehydrogenase (decarboxylating)
1.1.1.40
malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
1.1.1.85
3-isopropylmalate dehydrogenase
|
–
–
–
–
|
BMK
|
| |
BRENDA:
BR29303;
BS355850
KEGG:
R00216
MetaCyc:
MALIC-NADP-RXN
|
|
|
|
(S)-malate + NADP+ <=> H+ + NADPH + oxaloacetate
|
1.1.1.299
malate dehydrogenase [NAD(P)+]
1.1.1.37
malate dehydrogenase
1.1.1.375
L-2-hydroxycarboxylate dehydrogenase [NAD(P)+]
1.1.1.79
glyoxylate reductase (NADP+)
1.1.1.81
hydroxypyruvate reductase
1.1.1.82
malate dehydrogenase (NADP+)
|
–
–
–
–
–
–
|
BMK
|
| |
BRENDA:
BR29342;
BS188648
KEGG:
R00343
MetaCyc:
MALATE-DEHYDROGENASE-NADP+-RXN;
RXN-10813
SABIO-RK:
143
|
|
|
|
(S)-malate <=> fumarate + H2O
|
4.2.1.2
fumarate hydratase
4.2.1.34
(S)-2-methylmalate dehydratase
|
–
–
|
BMK
|
| |
BRENDA:
BR3389
KEGG:
R01082
MetaCyc:
FUMHYDR-RXN
SABIO-RK:
256
|
|
|
|
(S)-malate + 1-O-sinapoyl-beta-D-glucose <=> sinapoyl-L-malate + D-glucose
|
2.3.1.92
sinapoylglucose---malate O-sinapoyltransferase
|
–
|
MK
|
| |
BRENDA:
BR44095
KEGG:
R03323
MetaCyc:
2.3.1.92-RXN
|
|
|
|
acetyl-CoA + H2O + glyoxylate <=> H+ + (S)-malate + CoA
|
2.3.3.9
malate synthase
4.1.3.1
isocitrate lyase
|
–
–
|
BMK
|
| |
BRENDA:
BR47548;
BS381320
KEGG:
R00472
MetaCyc:
MALSYN-RXN
SABIO-RK:
152
|
|
|
|
succinyl-CoA + (S)-malate <=> succinate + (3S)-3-carboxy-3-hydroxypropanoyl-CoA
|
2.8.3.18
succinyl-CoA:acetate CoA-transferase
2.8.3.22
succinyl-CoA---L-malate CoA-transferase
|
–
–
|
MK
|
| |
BRENDA:
BR50973
KEGG:
R00406
MetaCyc:
RXN-8964
|
|
|
|
(3S)-3-carboxy-3-hydroxypropanoyl-CoA + H2O <=> (S)-malate + CoA + H+
|
3.1.2.30
(3S)-malyl-CoA thioesterase
|
–
|
BMK
|
| |
BRENDA:
BR50984
KEGG:
R10612
MetaCyc:
RXN-14937
|
|
|
|
(S)-malate + H+ <=> L-lactate + CO2
|
4.1.1.101
malolactic enzyme
|
–
|
MK
|
| |
BRENDA:
BR51422
KEGG:
R11074
MetaCyc:
RXN-16819
SABIO-RK:
12493
|
|
|
|
caffeoyl-CoA + (S)-malate <=> phaselic_acid + CoA
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
|
–
|
M
|
| |
BRENDA:
BS408813
MetaCyc:
RXN-10825
|
|
|
|
(S)-malate + CoA + ATP <=> phosphate + (3S)-3-carboxy-3-hydroxypropanoyl-CoA + ADP
|
6.2.1.5
succinate---CoA ligase (ADP-forming)
6.2.1.9
malate---CoA ligase
|
–
–
|
BMK
|
| |
BRENDA:
BR92;
BS428301
KEGG:
R01256
MetaCyc:
MALATE--COA-LIGASE-RXN
|
|
|
|
L-lactate + oxaloacetate <=> pyruvate + (S)-malate
|
1.1.99.7
lactate---malate transhydrogenase
|
–
|
K
|
| |
BRENDA:
BR29380;
BS451175
KEGG:
R01447
MetaCyc:
LACTATE-MALATE-TRANSHYDROGENASE-RXN
|
|
|
|
(S)-malate + a_quinone <=> oxaloacetate + a_quinol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
BK
|
| |
BRENDA:
BR49054;
BS421758
KEGG:
R00361
|
|
|
|
(S)-malate + O2 <=> oxaloacetate + H2O2
|
1.1.5.4
malate dehydrogenase (quinone)
1.13.12.4
lactate 2-monooxygenase
|
–
–
|
|
| |
BRENDA:
BS188783
KEGG:
R00360
|
|
|
|
(S)-malate + 3-acetylpyridine_adenine_dinucleotide <=> oxaloacetate + reduced_acetylpyridine_adenine_dinucleotide
|
1.1.1.37
malate dehydrogenase
|
–
|
|
| |
BRENDA:
BS373603
SABIO-RK:
10057
|
|
|
|
(S)-malate + 3-acetylpyridine_adenine_dinucleotide <=> oxaloacetate + 3-acetylnicotinamide-NADH + H+
|
1.1.1.37
malate dehydrogenase
|
–
|
|
| |
BRENDA:
BS451048
SABIO-RK:
10051
|
|
|
|
(S)-malate + deamido-NAD+ <=> oxaloacetate + deamino-NADH + H+
|
1.1.1.37
malate dehydrogenase
|
–
|
|
| |
BRENDA:
BS451049
SABIO-RK:
10069
|
|
|
|
(S)-malate + thio-NAD+ <=> oxaloacetate + thio-NADH + H+
|
1.1.1.37
malate dehydrogenase
|
–
|
|
| |
BRENDA:
BS451050
SABIO-RK:
10064
|
|
|
|
(S)-malate + FAD <=> oxaloacetate + FADH2
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
K
|
| |
KEGG:
R01257
|
|
|
|
electron-transfer_quinone + (S)-malate <=> electron-transfer_quinol + oxaloacetate
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
M
|
| |
MetaCyc:
MALATE-DEHYDROGENASE-ACCEPTOR-RXN
|
|
|
|
oxaloacetate + H+ + e- <=> (S)-malate
|
not assigned
|
–
|
|
| |
MetaCyc:
RXN-16329
|
|
|
|
menaquinone-9(2H) + (S)-malate <=> menaquinol-9 + oxaloacetate
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
MetaCyc:
RXN-21557
|
|
|
|
(3R)-3-hydroxy-4-oxobutanoate + NADP+ + H2O <=> (S)-malate + NADPH + H+
|
1.2.1.4
aldehyde dehydrogenase (NADP+)
|
–
|
M
|
| |
MetaCyc:
RXN-6002
|
|
|
|
UDP-N-acetyl-D-glucosamine + (S)-malate <=> (S)-malyl_N-acetyl-alpha-D-glucosaminide + UDP + H+
|
2.4.1.M61
|
–
|
M
|
| |
MetaCyc:
RXN8J2-1
|
|
|
|
(S)-malate + menaquinone <=> oxaloacetate + menaquinol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
M
|
| |
MetaCyc:
RXNI-3
|
|
|
|
succinate + (S)-malate <=> (S)-malate + succinate
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-106B
|
|
|
|
H+ + (S)-malate <=> H+ + (S)-malate
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-121A
|
|
|
|
(S)-malate <=> (S)-malate
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-224
|
|
|
|
(S)-malate <=> (S)-malate
|
not assigned
|
–
|
|
| |
MetaCyc:
TRANS-RXN-225
|
|
|
|
(S)-malate <=> (S)-malate
|
not assigned
|
–
|
M
|
| |
MetaCyc:
TRANS-RXN-374
|
|
|
|
GTP + (S)-malate + CoA <=> GDP + phosphate + (3S)-3-carboxy-3-hydroxypropanoyl-CoA
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
|
| |
BRENDA:
BS443613
|
|
|
|
L-2-hydroxysuccinamate + H2O <=> (S)-malate + NH3
|
3.5.1.3
omega-amidase
|
–
|
|
| |
BRENDA:
BS450123
|
|
|
|
4-coumaroyl-CoA + (S)-malate <=> CoA + 2-O-(4-coumaryl)-L-malate
|
2.3.1.133
shikimate O-hydroxycinnamoyltransferase
|
–
|
|
| |
BRENDA:
BS408079
|
|
|
|
1-O-caffeoyl-beta-D-glucose + (S)-malate <=> D-glucose + phaselic_acid
|
2.3.1.92
sinapoylglucose---malate O-sinapoyltransferase
|
–
|
|
| |
BRENDA:
BS321486
|
|
|
|
p-coumaroyl-beta-D-glucose + (S)-malate <=> D-glucose + 4-coumaroyl-L-malate
|
2.3.1.92
sinapoylglucose---malate O-sinapoyltransferase
|
–
|
|
| |
BRENDA:
BS321488
|
|
|
|
1-O-feruloyl-beta-D-glucose + (S)-malate <=> D-glucose + feruloyl-L-malate
|
2.3.1.92
sinapoylglucose---malate O-sinapoyltransferase
|
–
|
|
| |
BRENDA:
BS321485
|
|
|
|
(S)-malate + NAD+ <=> acetate + CO2 + H2 + NADH
|
1.1.1.37
malate dehydrogenase
|
–
|
|
| |
BRENDA:
BS188090
|
|
|
|
pyruvate + NAD+ + HCO3- <=> (S)-malate + NADH
|
1.1.1.39
malate dehydrogenase (decarboxylating)
|
–
|
|
| |
BRENDA:
BS398232
|
|
|
|
(S)-malate <=> glyoxylate + acetate
|
4.1.3.1
isocitrate lyase
|
–
|
|
| |
BRENDA:
BS380821
|
|
|
|
(S)-malate + menaquinone-1 <=> oxaloacetate + menaquinol-1
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS422235
|
|
|
|
(S)-malate + ubiquinone-9 <=> oxaloacetate + ubiquinol-9
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403148
|
|
|
|
(S)-malate + duroquinone <=> oxaloacetate + duroquinol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS188940
|
|
|
|
(S)-malate + menadione <=> oxaloacetate + 2-Hydroxy-1,4-naphthoquinone
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403150
|
|
|
|
(S)-malate + 2,6-dichlorophenolindophenol <=> oxaloacetate + reduced_2,6-dichlorophenolindophenol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS188942
|
|
|
|
(S)-malate + oxidized_2,6-dichlorophenolindophenol <=> oxaloacetate + reduced_2,6-dichlorophenolindophenol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403143
|
|
|
|
(S)-malate + vitamin_K <=> oxaloacetate + vitamin_KH2
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403149
|
|
|
|
(S)-malate + ubiquinone <=> oxaloacetate + ubiquinol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403145
|
|
|
|
(S)-malate + 2,3-dimethoxy-5-methyl-1,4-benzoquinone <=> oxaloacetate + reduced_coenzyme_Q0
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403144
|
|
|
|
(S)-malate + ubiquinone-6 <=> oxaloacetate + ubiquinol-6
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS403147
|
|
|
|
(S)-malate + 2,3-dimethyl-1,4-naphthoquinone <=> oxaloacetate + 2,3-dimethyl-1,4-naphthoquinol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS422233
|
|
|
|
(S)-malate + 2,6-dichlorphenolindophenol <=> oxaloacetate + reduced_2,6-dichlorphenolindophenol
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
|
| |
BRENDA:
BS389044
|
|
|
|
(S)-malate + acceptor <=> oxaloacetate + reduced_acceptor
|
1.1.5.4
malate dehydrogenase (quinone)
|
–
|
B
|
| |
BRENDA:
BS402298
|
|
|
|
oxaloacetate + H+ + deamino-NADH <=> (S)-malate + nicotinamide_hypoxanthine_dinucleotide
|
1.1.1.37
malate dehydrogenase
|
–
|
|
| |
SABIO-RK:
10308
|
|
|
|
(S)-malate + acetyl-CoA <=> (3S)-3-carboxy-3-hydroxypropanoyl-CoA + acetate
|
2.8.3.18
succinyl-CoA:acetate CoA-transferase
|
–
|
|
| |
SABIO-RK:
14388
|
|
